A new study links this popular diet with lower blood pressure — and reduced cardiac injury and strain
‘Our study represents some of the strongest evidence that diet directly impacts cardiac damage, and our findings show that dietary interventions can improve cardiovascular risk factors’
Exercise and certain diets may improve your cardiac health in unexpected ways. GETTY IMAGES
Does the DASH diet have hidden health effects?
Researchers from Beth Israel Deaconess Medical Center examined three cardiovascular indicators to determine if — and how — diet directly impacts cardiac health. They analyzed blood samples from clinical-trial participants who stuck to strict dietary regimens and found that the DASH diet, already shown to lower blood pressure, also reduces inflammation.
The conclusion, published in the Journal of the American College of Cardiology, also found that the DASH diet — whether or not it’s adhered to in conjunction with a low-sodium diet — reduces heart injury and strain.
The DASH diet, short for Dietary Approaches to Stop Hypertension, recommends fruits, vegetables, nuts, whole grains, poultry, fish and low-fat dairy products, while restricting salt, red meat, sweets and sugar-sweetened beverages.
Among trial participants on the DASH diet, biomarkers linked to cardiac damage and inflammation fell by 18% and 13%, respectively. Participants combining the DASH diet with reduced-sodium behavior had the most pronounced reductions in both cardiac injury and stress — 20% and 23%, respectively — although inflammation was not significantly impacted.
‘Our study represents some of the strongest evidence that diet directly impacts cardiac damage.’
“Our study represents some of the strongest evidence that diet directly impacts cardiac damage, and our findings show that dietary interventions can improve cardiovascular risk factors in a relatively short time period,” said Stephen Juraschek, an assistant professor of medicine at Beth Israel Deaconess Medical Center and Harvard Medical School.
“The data reinforce the importance of a lifestyle that includes a reduced-sodium, DASH diet rich in fruits, vegetables and whole grains to minimize cardiac damage over time,” said Juraschek, a co-author on the study.
The Mediterranean diet focuses on olive oil rich in healthy omega-3 fatty acids, fruits and vegetables, whole grains and lean protein like fish and chicken, with the occasional piece of red meat. It also emphasizes beans, nuts, legumes, and flavorful herbs and spices, as well as cheese, yogurt and a glass of red wine in moderation.
Unlike the Mediterranean diet, the DASH diet emphasizes fruits, vegetables, low-fat dairy products and nuts while limiting saturated fats, total fat, cholesterol, red meat, sweets and sugar-containing beverages, Juraschek and his co-authors said. It was developed in the 1990s with the specific goal of lowering blood pressure, and has been shown to help lower the chances of stroke and diabetes.
Blood pressure is one of the best predictors of cardiovascular health, and cardiovascular disease is the No. 1 killer of people in the U.S. Previous research also suggested that a lack of sleep may offer one possible explanation for why sleep problems have been shown to increase the risk of heart attack, stroke and even death from cardiovascular disease.
Once More For the People in the Back: You Cannot Negotiate or Compromise With the Republican Party
Jack Holmes May 20, 2021
Photo credit: Drew Angerer – Getty Images
Somehow, after everything, there remain creatures in Washington, D.C. obsessed with bipartisan compromise. One of our two major political parties has lined up in opposition to renewing what’s left of the Voting Rights Act, which swept through Congress on a strong bipartisan basis in the Bush years, when it actually still had some teeth. The same party’s Arizona affiliate is engaged in a circus “audit” of that state’s election results because they didn’t like who won. They’ve also responded to the 2020 election, which many Republicans continue to Just Ask Questions about, by passing hundreds of restrictive voter laws in state legislatures across the country. Through this and gerrymandering and court-packing and the undemocratic features of the Senate and the Electoral College, the party has devoted itself, root and branch, to clinging to power without crafting an agenda that actually appeals to a majority of citizens.
But even beyond any of that, they just submarined their own shared Bipartisan Bill to establish a commission to look into an attack on their own place of work earlier this year. If a mob broke into your company’s offices and ransacked the place, chanting that they wanted to hang the vice president of the firm, would the VP’s putative friends—and brother!—shut down an inquiry into what happened? This is not normal behavior, and it’s not the behavior of an organization whose members can be reasoned with. (As David Freedlander pointed out, House Republican Leader Kevin McCarthy used to back a Commission as a desperate escape from impeaching Donald Trump for his crimes against the republic. Now he’s against this, too. It’s almost like he’s not actually interested in any kind of accountability.) There will be no Bipartisan Compromise so long as the Republican Party clings to the increasingly kaleidoscopic fever dreams blasting out of the right-wing infotainment vortex. As my colleague, Charles P. Pierce, wrote, the Democrats will need to go it alone on a January 6 commission. In truth, they’ll have to go it alone on everything.
Photo credit: Drew Angerer – Getty Images
This ought to have been obvious before. In the Senate, Mitch McConnell has proven to be the most cynical operator that Washington, D.C. has seen in some time, and that’s saying something. McCarthy, in the House, is as craven as he is dense. And the party has a track record, going back to the Obama years, of demanding bipartisan consultation, extracting concessions and watering down bills, then voting against them anyway. This is what happened with the January 6 commission: Republicans got pretty much everything they wanted, and they still shut it down. They will do the same with the American Jobs Plan. As Catherine Rampell brilliantly laid out in the Washington Post, the initial lowball counterproposal they offered was actually vastly inflated. Their aim is to hack away at the bill, then vote against it. And you can probably forget about even that level of commitment to the American Families Plan. Josh Hawley might have some family-benefits proposals, and so might Mitt Romney on the party’s other wing, but when it gets to crunch time, you can expect at least the former (and very possibly the latter) to vote against the plan and fist-pump at the faithful.
This is an American political ecosystem where shame has ceased to function as a social force and, in fact, shamelessness has become a political superpower. To survive and thrive in the entirely degraded post-Trump Republican Party—the culmination of 40-plus years of self-replicating insanity—you cannot have any compunction about lying your ass off and acting in continual, ceaseless bad faith. There are people in this party who voted against the American Rescue Plan and then went bragging to their constituents about all the relief they’d brought home. Flip-flopping is passé. You now have to be able to juggle multiple contradictory positions at once. John Katko made the mistake Wednesday of thinking any principle—even that an attack on their own workplace should be investigated by Congress—was durable enough to survive the gauntlet of self-serving nonsense. Democrats should do their own commission, and then they should do their own bills. This will require Joe Manchin and Kyrsten Sinema coming back to reality, and seeing all of the above for it is before signing off on filibuster reform. You cannot negotiate with the void.
Republicans Threw Their Own Guy Deep Under the Bus to Avoid a January 6 Commission
Every speaker tried to find a polite way to call John Katko either a rube or a sucker. The end result is that Democrats will need to go on their own.
By Charles P. Pierce May 20, 2021
CAROLINE BREHMAN/GETTY IMAGES
The It-Didn’t-Start-With-Trump element of the Republican recalcitrance on a proposed bipartisan (Gawd!) commission to investigate the January 6 insurrection is to recall that George W. Bush did all he could to derail the 9/11 commission that everyone now pretends to adore, and that C-Plus Augustus refused to testify under oath to that commission, and wouldn’t even sit for an unrecorded interview except in the White House with Dick Cheney, father of St. Liz of the Holy Soundbite, sitting next to him working the levers. And let’s not even get into the government-wide stonewalling of the Iran-Contra investigations before that, and let’s also remember that there were 33 investigations into Benghazi, BENGHAZI, BENGHAZI!
However, when Mitch McConnell came out on Tuesday as the devious reptile he’s always been, and announced that he was joining House Republican honcho Kevin McCarthy over in Coward’s Corner, the difference was an order of magnitude. These guys were shirking their constitutional obligation and abandoning their moral compasses because a) they lead a party that is very likely complicit in the events, and b) they’re doing so to cover for a crook and a liar who’s in so many crosshairs he looks like Bonnie and Clyde at the end of that movie.
After careful consideration, I’ve made the decision to oppose the House Democrats’ slanted and unbalanced proposal for another commission to study the events of January 6…So, Mr. President, it’s not at all clear what new facts are additional—or additional investigation yet another commission could actually lay on top of existing efforts by law enforcement and Congress. The facts have come out and they’ll continue to come out. What is clear, is that House Democrats have handled this proposal in partisan bad faith going right back to the beginning. From initially offering a laughably partisan starting point to continuing to insist on various other features under the hood that are designed to centralize control over the commission’s process and its conclusions in Democratic hands.
Mitch, my dude, this isn’t a job for grown-ups. And let us all wave farewell to Rep. John Katko, the Republican co-sponsor of the “bipartisan” commission proposal, as he disappears forever under a bus.
Later Wednesday afternoon, debate in the House began on the resolution establishing the commission. The overarching impressions were that, in the debate, the Democrats led with age and the Republicans led with crazy. The first three speakers in defense of the resolution—Nancy Pelosi, Bennie Thompson, and Steny Hoyer—are a combined 235 years old. The Republican side led off with Marjorie Taylor Greene, Louis Gohmert, and some guy from North Carolina named Sam Bishop, who wanted to make sure everybody knew that what happened on January 6.
Let me say this, if it was an insurrection, it was the worst example of an insurrection in the history of mankind. It was a riot. It was a mob. And it was significant. And it was troublesome. But this is not bipartisanship. And I fear that the gentleman from New York may find that he has been played.
Personally, I think the passel of elderly Communist inebriates who tried to overthrow future Pizza Hut spokesman Mikhail Gorbachev back in August of 1991 are still the gold standard for insurrectionist clownery. (They got faced down by Boris Yeltsin, reportedly because, against all possible odds, some of them were drunker than Yeltsin was.) That, however, is beside the point. I would draw your attention to that last sentence in which John Katko returns to his place under the wheels.
Mitch McConnell joined Kevin McCarthy in the Coward’s Corner. KENT NISHIMURA/GETTY IMAGES
Watching Katko straddle the crazy to get the resolution he co-sponsored passed made you fear for every hamstring the man owns. Speaker after speaker tried to find polite ways to call Katko either a rube or a sucker. Meanwhile, the Democrats, in the person of co-sponsor Thompson, seem convinced that the fact that the resolution is “bipartisan” has some ultimate legislative salience in the Congress, and some ultimate political salience in the country, which is something I doubt profoundly. People don’t give a fck about bipartisanship. It’s neither a dealmaker nor a dealbreaker. It’s a green-room amenity, like sodas and a crudité plate. Thankfully, Rep. Tim Ryan showed up to inveigh against the futility of it all.
To the other 90% of our friends on the other side of the aisle, holy cow. Incoherence. No idea what you’re talking about. Benghazi, you guys chased the former Secretary of State all over the country, spent millions of dollars. We have people scaling the Capitol, hitting the Capitol police with lead pipes across the head and we can’t get bipartisanship. What else has to happen in this country? Cops, this is a slap in the face to cops across America. If we’re going to take on China, reverse climate change, we need two political parties in this country that are both living in reality and you ain’t one of them.
To which Katko responded in his best hall-monitor voice that things were getting impermissibly partisan and emotional. Because, when you come right down to it, John Katko is a Republican, too. At loose moments, he let that slip through. For example, the regular GOP stance on the commission is that it ought to investigate the disturbances last summer following the murder of George Floyd. (Rep. Marjorie Taylor Greene ranted about them in her one minute of debate time.) But Katko tried another tack.
And of course we can’t forget the 2017 terrorist attack against Republican members of Congress during practice for the congressional baseball game. Were it not for the officers involved, there would be scores of dead congressmen. That’s the plain truth.
This is a matter of comparing apples and salamanders. The 2017 episode was the work of one man, James Hodgkinson, and he was killed by the officers at the scene. There was a Secret Service investigation almost immediately after the shooting. As far as I know, there haven’t even been rumors of other people involved in the shooting. Hodgkinson was vocal in his dislike of Republicans and clearly came to the ballfield to attack them that morning, but he did it all on his own. An awful event, certainly, but if Katko thinks a 1/6 commission should examine it, then he’s as invested in delay and deflection as Greene is.
And, unless Mitch McConnell is taken off to glory and replaced by Zombie Paul Douglas, this thing is as dead as Kelsey’s nuts in the Senate anyway. Ten Republicans would have to vote for it and, well, no. It’s time for Democrats simply to put together a select committee of their own, issue subpoenas, and let the chips fall.
County tells Arizona Senate to keep files, threatens lawsuit
Jonathan J. Cooper May 21, 2021
PHOENIX (AP) — Maricopa County officials on Friday directed the Arizona Senate and the auditors it hired to review the county’s 2020 election count to preserve documents for a possible lawsuit.
The county made the demand in a letter after the auditors refused to back down from their claim that the county destroyed evidence by deleting an election database. The GOP-controlled Board of Supervisors and Republican Recorder Stephen Richer, one of the top election officials, say the claim is false.
County officials earlier this week said they might consider filing a defamation lawsuit if the Senate President Karen Fann and the auditors don’t retract the allegation files were deleted.
“Because of the wrongful accusations that the County destroyed evidence, the County or its elected officers may now be subject to, or have, legal claims,” the county’s chief litigation attorney, Tom Liddy, wrote in a letter to Senate President Karen Fann, a Republican from Prescott.
Senate Republicans are overseeing an unprecedented partisan audit of the 2020 election in Maricopa County, including a hand recount of 2.1 million ballots and a review of voting machines and other data. Fann claimed the database was deleted, which a twitter account tied to the audit called “spoliation of evidence.” Former President Donald Trump amplified the claim in a statement last weekend.
County officials said Monday that no databases or directories were deleted and laid out a detailed explanation for why they believe the auditors couldn’t find them, accusing the auditors of ineptitude. The next day, a data forensics consultant on the audit team said he was able to “recover” the files, and the audit’s Twitter account later repeated the claim that files were deleted.
The letter directs Fann and anyone working on the audit to preserve any records related to it, including emails and text messages, computer files, cellphones and other devices.
The audit will not change the election result. But Trump and many of his supporters believe it will support their baseless claim that Trump’s loss was marred by fraud.
‘Impending disaster.’ Worsening algae bloom on Lake Okeechobee threatens coasts again
Adriana Brasileiro May 14, 2021
The scene at Pahokee marina on Lake Okeechobee last week was a warning sign: A thick mat of algae in various shades of green, brown, gray and fluorescent blue covered the area around boat slips. In some spots, the gunk was so dense it stuck out two inches above the water.
Elsewhere on the lake, the algae wasn’t as chunky, but satellite photos were just as shocking: NOAA monitoring images on Wednesday showed nearly two-thirds of the lake, or 500 square miles, were covered with blue-green algae, the potentially toxic stuff that has fouled rivers and canals in the west and east coasts of Florida in past years, killing fish and scaring tourists away. Green streaks of algae are already visible moving down from the Moore Haven lock on the Caloosahatchee River, which has received Lake Okeechobee water releases in recent weeks to lower lake levels.
Is South Florida in for another summer of slime? The answer has a lot to do with how much water will be flushed from the lake to Florida’s west and east coasts. Already, Lake Okeechobee is at 13.6 feet, 2.5 feet higher than what it was at this time last year. Forecasters are predicting a “well above average” hurricane season this year.
“This is an impending disaster,” said John Cassani, of Calusa Waterkeeper. He and other activists are asking Gov. Ron DeSantis to declare a state of emergency to protect the Caloosahatchee from harmful lake discharges as the rainy season approaches and the need to lower water levels will be unavoidable. “Think of the lake as a giant cesspool being flushed into the Caloosahatchee every day with no end in sight. It’s a catastrophic situation.”
Workers from Breen Aquatics vacuum up thick blue-green algae as they try to clean up blooms at the Pahokee Marina on May 3.
The bloom, which expanded quickly over the past few weeks as temperatures rose, is fueling heated debate about how the U.S. Army Corps of Engineers should manage lake waters considering conflicting interests: the need to send water south for Everglades restoration and the guarantee of sufficient supplies for farming while also managing flood protection structures such as its aging Herbert Hoover dike.
The Corps is currently revising its lake management policies to take into account a massive $1.8 billion upgrade of the dike that is scheduled to be completed next year as well as Everglades restoration projects that will come online in the next few years. The projects include a vast reservoir and stormwater treatment area that, once completed in 2023, will allow managers to send more water south when lake levels rise, reducing discharges to estuaries on the east and west. The aim is to produce water clean enough to replenish the Everglades amid efforts to recreate something close to the original flow of the River of Grass, going south through Shark Valley in Everglades National Park, taking much-needed fresh water all the way south to Florida Bay.
The Corps recently presented five conceptual plans for its new Lake Okeechobee System Operating Manual (LOSOM) that will receive public comment before more detailed proposals are presented in July.
But water quality activists want the state to act now under an emergency order to try to avoid a repeat of the devastating 2018 season when massive blooms of cyanobacteria in the lake were discharged to estuaries, killing marine life and making pets and even people sick. The blooms coincided with a widespread red tide that started in the Gulf Coast but spread as far as the Panhandle and St. Lucie County on the Atlantic coast, fouling beaches with dead fish and hundreds of marine animal carcasses.
On Friday the Corps said it will reduce discharges to the Caloosahatchee to 1,500 cubic feet per second from the current 2,000 cfs as a result of the blooms. Col. Andrew Kelly, the Corps commander for Florida, said releases will be made in pulses to try to flush out algae-laden freshwater and allow for water with higher salinity levels to move up the river.
“Some types of algae don’t do as well in higher salinity so we are trying to get some of the higher salinity up into the Caloosahatchee, which will support the degradation of some of that algae, by doing a pulse release of freshwater,” he said during a call with reporters.
Send ‘all that you can’ south
Friends of the Everglades, the Center for Biological Diversity, the Conservancy of South Florida and several water quality advocacy groups sent DeSantis a letter earlier this week saying the state must waive restrictions that stop water managers from moving more water south into conservation areas. Some of those restrictions exist to make sure the water is clean enough to go into conservation areas and beyond, into the Everglades.
DeSantis, who flew over Lake Okeechobee earlier this week to check on the problem, said he asked the District to send “all that you can south,” but didn’t respond to the request for an emergency order. He said he expects the Corps to come up with “a good regulation schedule that balances the equities” and mitigates negative impacts to coastal communities in the summer.
NOAA satellite images showed that cyanobacteria covered about 500 square miles of the lake earlier this week.
Treasure Coast Rep. Brian Mast threatened to sue the Corps to stop the discharges in an interview with CBS 12 on Thursday.
During a board meeting on Thursday, District staff said water conservation areas south of the lake were mostly full or couldn’t receive water because they were in the process of being restored or had projects under construction. Water Conservation Area 3, for instance, is undergoing restoration work after Tropical Storm Eta last year filled marshes to the brim, flooding tree islands and forcing deer to crowd onto levees to survive.
Communities around Lake Okeechobee said their needs must be taken into account. Hendry County Commissioner Ramon Iglesias expressed concern about a schedule that allows too much discretion and flexibility by the Corps every year. He said his fishing and farming community needs certainty so that residents can better plan their lives.
“No schedule should singularly prioritize the loudest people in the room,” Iglesias said during public comments. “We can have a schedule that takes everyone’s concerns into consideration, but not at the expense of my community or any other Floridian that depends on the lake when they need it for drinking, for fishing, for recreating, for farming and even for the environment.”
Sending water south to the Everglades during the dry season is common sense, but it’s important to hold the District accountable for how it manages water in the storm treatment areas, said Eve Samples from Friends of the Everglades. She said most of the water treated in these marsh-like reservoirs is runoff from farms and not water from the lake.
“Why is EAA farm runoff being given priority capacity in taxpayer-funded stormwater treatment areas when STAs could be cleaning water from the lake and sparing people east and west from exposure to these cyanotoxins?” Samples asked.
A decades-old fight for water
Organizations that defend agriculture said everyone is to blame. Nyla Pipes, a sugar industry advocate at One Florida Foundation, said nutrients come from multiple sources and all of them need to be addressed. She said people often blame agriculture because “the public really doesn’t understand that algae is already in our water” and it only gets out of control when there are too many nutrients.
“All this finger pointing … we need to be looking in the mirror because it’s all of us,” she said.
Blue-green algae blooms were observed in nearly two-thirds of the lake earlier this week.
The Everglades Foundation has said it’s about time the state started to manage the lake in a more equitable way and provided its own LOSOM idea to the Corps.
“Currently, we’re not managing Lake Okeechobee in a balanced way. It’s really managed for the needs of agriculture south of the lake, which is primarily sugar. They get the water when they want it. And when it rains, they dump all their stormwater into the Everglades,” said the foundation’s chief science officer, Stephen Davis.
The discussion highlighted the decades-old conflicts in lake water uses and needs. While higher levels benefit farmers that have for decades relied on consistently delivered lake water for their fields, environmentalists and coastal communities say the lake should be kept lower in the dry season and higher in the wet season, to prevent discharges of polluted water to the St. Lucie estuary in the east and the Caloosahatchee to the west.
To prevent a breach on the aging dike when there’s too much water in the lake, the Corps has historically discharged the excess to coastal estuaries. But Lake O is growing increasingly polluted with fertilizer from surrounding farms and communities, and decades of phosphorus and nitrogen that has accumulated on the bottom.
This “legacy pollution” can get stirred up by strong winds over the shallow lake, releasing nutrients that feed blooms. Davis said that’s probably the case now, as blooms are happening early in the season.
“Typically, we don’t see this much algal coverage on the lake until June or July, when we have the longest day lengths,” and sunlight drives the photosynthesis that makes algae grow and reproduce, he said.
Scuba divers begin 6-month effort to rid Lake Tahoe of trash
1 / 4
Tahoe Cleanup-Scuba Divers
This photo provided by Clean Up The Lake shows a scuba diver beneath the surface of Lake Tahoe, cleaning up trash on Friday, May 14, 2021. A team of scuba divers on Friday completed the first dive of a massive, six-month effort to rid the popular Lake Tahoe of fishing rods, tires, aluminum cans, beer bottles and other trash accumulating underwater. (Clean Up The Lake via AP)
SOUTH LAKE TAHOE, Calif. (AP) — A team of scuba divers on Friday completed the first dive of a massive, six-month effort to rid the popular Lake Tahoe of fishing rods, tires, aluminum cans, beer bottles and other trash accumulating underwater.
The team of between five and 10 divers plans to look for trash along the entire 72 miles (115 kilometers) of shoreline and dig it out in an endeavor that could be the largest trash cleanup in Lake Tahoe’s history, said Colin West, a diver and filmmaker who founded Clean Up the Lake, the nonprofit spearheading the project.
“We are still learning not to be so wasteful. But unfortunately, as a species we still are, and there are a lot of things down there,” West said after completing the first dive.
The team collected about 200 pounds (90 kilograms) of garbage during their one-tank session and found 20 large or heavy items, including buckets filled with cement and car bumpers, that will have to be retrieved later by a boat with a crane, he said.
They plan to dive three days a week down to 25 feet (7 meters) in depth. The clean-up effort will cost $250,000 — money the nonprofit has collected through grants — and will last through November.
West started doing beach cleanups along the lake after visiting Belize and seeing beaches there littered with trash. But in 2018, after a diver friend told him he and others had collected 600 pounds (272 kilograms) of garbage from the waters on Tahoe’s eastern shore, he decided to focus on the trash in the water.
“I was blown away, and we started researching and going underneath the surface and we kept pulling up trash and more trash,” said West, who lives in Stateline, Nevada.
In a survey dive on September 2019, his team removed more than 300 pounds (136 kilograms) of debris from Lake Tahoe’s eastern shore and planned to launch his clean-up along the whole shoreline last year. The pandemic delayed those plans.
But the group of volunteers, which includes not only divers but support crew on kayaks, boats and jet skis, continued diving and cleaning both Lake Tahoe and nearby Donner Lake. By the end of the last summer, they had collected more than 4 tons (4 metric tons) of trash from both lakes.
Heart study: Low- and regular-dose aspirin safe, effective
Marilynn Marchione May 15, 2021
An unusual study that had thousands of heart disease patients enroll themselves and track their health online as they took low- or regular-strength aspirin concludes that both doses seem equally safe and effective for preventing additional heart problems and strokes.
But there’s a big caveat: People had such a strong preference for the lower dose that it’s unclear if the results can establish that the treatments are truly equivalent, some independent experts said. Half who were told to take the higher dose took the lower one instead or quit using aspirin altogether.
“Patients basically decided for themselves” what they wanted to take because they bought the aspirin on their own, said Dr. Salim Virani, a cardiologist at Baylor College of Medicine in Houston who had no role in the study.
Still, the results show there’s little reason to take the higher dose, 325 milligrams, which many doctors assumed would work better than 81-milligram “baby aspirin,” he said.
Results were published Saturday by the New England Journal of Medicine and discussed at an American College of Cardiology conference.
Aspirin helps prevent blood clots, but it’s not recommended for healthy people who have not yet developed heart disease because it carries a risk of bleeding. Its benefits are clear, though, for folks who already have had a heart attack, bypass surgery or clogged arteries requiring a stent.
But the best dose isn’t known, and the study aimed to compare them in a real-world setting. The study was funded by the Patient-Centered Outcomes Research Institute, created under the 2010 Patient Protection and Affordable Care Act to help patients make informed decisions about health care.
About 15,000 people received invitations to join through the mail, email or a phone call and enrolled on a website where they returned every three to six months for follow-up. A network of participating health centers supplied medical information on participants from their electronic records and insurance claims.
The participants were randomly assigned to take low- or regular-dose aspirin, which they bought over the counter. Nearly all were taking aspirin before the study began and 85% were already on a low dose, so “it was an uphill task right from the get-go” to get people to use the dose they were told, Virani said.
After roughly two years, about 7% of each group had died or been hospitalized for a heart attack or a stroke. Safety results also were similar — less than 1% had major bleeding requiring hospitalization and a transfusion.
Nearly 41% of those assigned to take the higher dose switched at some point to the lower one, and that high rate “could have obscured a true difference” in safety or effectiveness, Colin Baigent, a medical scientist at the University of Oxford in the United Kingdom, wrote in a commentary in the medical journal.
One study leader, Dr. Schuyler Jones of Duke University, said the study still provides valuable guidance. If patients are taking low-dose aspirin now, “staying on that dose instead of switching is the right choice,” he said. People doing well on 325 milligrams now may want to continue on that and should talk with their doctors if they have any concerns.
For new patients, “in general, we’re going to recommend starting the low dose,” Jones said.
Virani said people must remember that aspirin is a medicine and that even though it’s sold over the counter, patients shouldn’t make decisions on its use by themselves.
“Don’t change the dose or stop without talking to someone,” he warned. “This is important, especially for a therapy like aspirin.”
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
Republican lies have thrust America into its third revolution. We are a nation in crisis.
Carrie Cordero and Edward J. Larson
Angry supporters of President Donald Trump scale the west wall of the the U.S. Capitol in Washington on Jan. 6, 2021.
To read and listen to the headlines after House Republicans voted to remove Rep. Liz Cheney from her leadership post, one would think that the “turning point” in the Republican Party began with its denial of the 2020 election result after Nov. 3, or the Capitol insurrection on Jan. 6. Neither of those moments, however, is or was the actual turning point. Instead, the transformation one of the nation’s two major political parties took place well before each of those events. And the longer it takes for the public conversation to recognize how dramatically the Republican Party has already shifted, the longer it will take to develop a coherent civic strategy to protect U.S. democracy going forward.
And we do need a strategy, because this political crisis is not just the internal machinations of a single political party; it is a political crisis of a nation. Indeed, it might not be hyperbolic to characterize our present national state as in the midst of the third revolution.
Tectonic shift in the Republican Party
What was at first an acquiescence to Donald Trump since his nomination at the Republican National Convention in 2016 slowly became a public acceptance, and then an entanglement. Some who were slow to realize the tectonic shift taking place in the Republican Party over the past five years have awakened from their slumber in the wake of the attack on the Capitol. They are a little late. Those who thought they could wait out Trump’s presidential term before getting on the right side of history were wrong; the time for choosing in a way to actually affect the trajectory of the modern-day Republican Party was earlier.
One explanation for this delayed acknowledgement could be that even sophisticated political participants forget how quickly political parties can completely transform or disappear. Some political actors perhaps thought that they had more time. In the 1850s, a decade before the Civil War, the relative balance that had lasted for a generation between the two political parties – the Democrats and the Whigs – collapsed. The Whig Party disintegrated between 1852 and 1856. As this historic transformation shows, fundamental change to a political party need not take decades. It can happen in just a few years.
From left, Jared Kushner, Ivanka Trump, President Donald Trump and Japanese Prime Minister Shinzo Abe in Osaka in 2019.
From 2016-20, it appeared that the Republican Party might disintegrate like the Whigs. First, the GOP looked away as Trump relied on family members instead of government professionals as White House advisers. Second, midway through his term, the president fired or solicited the resignations of political appointees of his own party who had been confirmed by the Senate. He repeatedly turned on his own appointees, particularly when they sought to carry out their lawful functions. Third, the Republican convention in 2020 declined to adopt a political platform; instead, it allowed the party to reflect the whims of its highly personalized leader.
Since then, the vast majority of Republican voters and officials have embraced denial of the 2020 election results and refused to acknowledge the severity of the Jan.6 attack on the Capitol. These developments reveal that the Republican Party will not give up like the Whigs. The party will persevere, emboldened by taking pride in belligerence and transformed into a political movement that embraces fraud and deceit as fundamental to its survival and electoral success.
US democracy’s existential crisis
We are all familiar with the first American Revolution: an actual war, a rebellion for self-governance. But it was not long after that Thomas Jefferson called the election of 1800 the “second American revolution.” The election of the Democratic-Republicans over the Federalists set the course for the nation in Jefferson’s vision of American democracy, and permanently marginalized the Federalist Party and led to its ultimate replacement by the Whigs.
In the hours after the insurrection at the U.S. Capitol, former president Trump tweeted, “Remember this day forever!” Participants in the melee he incited openly invoked 1776.
American Revolution reenactment in Lexington, Mass., in 2006.
We will not know until after the 2022 midterms and the 2024 presidential election whether the result of 2020 set the nation on a path toward Democratic Party domination for a generation, like the election of 1800. But we think this moment in our nation’s history is best understood as the third American revolution – hopefully primarily of competing ideas and minimally of political violence – where the effective functioning of American elections and democratic institutions hangs in the balance.
It is no longer enough to characterize the present political crisis as an internal party dispute. Instead, we are witness to a political revolution that will define American society and governance for decades to come.
Carrie Cordero is the Robert M. Gates Senior Fellow at the Center for a New American Security and adjunct professor at Georgetown Law. Edward J. Larson is a Pulitzer Prize winning legal historian and a professor at Pepperdine University whose latest book is “Franklin & Washington: The Founding Partnership.“
FILE PHOTO: Nurse prepares to administer the AstraZeneca/Oxford vaccine against the COVID-19 at the Eka Kotebe General Hospital in Addis Ababa
LONDON (Reuters) – India’s export ban on COVID-19 shots risks dragging the battle against the pandemic “back to square one” unless wealthy nations step in to plug a gaping hole in the COVAX global vaccine-sharing scheme, health specialists said on Thursday.
COVAX, which is critical for poorer countries, relies on AstraZeneca shots made by the Serum Institute of India, the world’s biggest maker of vaccines. It was already around 100 million doses short of where it had planned to be when India halted exports a month ago amid a surge in infections there.
Rich countries with plentiful COVID-19 vaccine stocks must now share them immediately, at scale, the global experts said, otherwise the pandemic could be prolonged as the world struggles to contain a virus that is continuing to spread and mutate.
“It is a huge concern,” said Anna Marriott, health policy manager at the global charity Oxfam. She and others said it was imperative that wealthy countries and regions make good on their rhetoric and share excess vaccines now.
“The current approach that relies on a few pharma monopolies and a trickle of charity through COVAX is failing – and people are dying as a result.”
Reuters reported on Tuesday that India is extending its ban, meaning it is now unlikely to resume major exports before October.
Will Hall, global policy manager for the Wellcome global health trust, said COVAX’s heavy reliance on the Serum Institute left it vulnerable. India’s extension of its export ban made it even more crucial for rich countries to share doses via the scheme, he said, “not in six months’ time, not in a month’s time, but now”.
“We’re not going to beat this virus unless we think and act globally,” he added. “We all should be concerned about this – the more the virus continues to spread, the greater the risk of it mutating to a stage where our vaccines and treatments no longer work. If that happens we’re back to square one.”
A highly transmissible new variant of the novel coronavirus first identified in India has spread to several countries around the world.
‘VERY FEW OPTIONS’
COVAX aims to get vaccines to at least 20% of the populations of the more-than 90 low and middle-income countries signed up to receive the shots as donations. It has so far distributed about 65 million doses of mainly the AstraZeneca COVID-19 vaccine, many of them to Africa.
A spokeswoman for the GAVI vaccines alliance, which co-leads COVAX, said the facility was working hard to make up supplies.
“We’re trying to find different ways of making sure that those countries that have received the first dose are able to also receive a second dose and that vaccinations can continue,” she told Reuters. “What we need right now, to meet the immediate needs, is dose sharing.”
The United States said on Wednesday it would share a total of 20 million doses of Pfizer’s, Moderna’s and Johnson & Johnson’s vaccines by the end of June, donating a significant amount via COVAX, on top of 60 million AstraZeneca shots it had already planned to give to other countries.
EU trade commissioner Valdis Dombrovskis said this week that the bloc was working to significantly ramp up vaccine donations through COVAX in the second half of 2021. Vaccine sharing announced by EU member states has so far amounted to 11.1 million vaccines, he said, of which 9 million are being shared via COVAX.
Britain, meanwhile, will have enough surplus doses to fully vaccinate at least 50 million people in poorer countries once every adult at home has been fully vaccinated, according to analysis by UNICEF’s UK office last week.
The GAVI spokeswoman said COVAX’S reliance on the Serum Institute was based, largely, on its vast production capacity, ability to deliver at low cost and on assurances that it would be able to produce the millions of doses needed at speed.
“It always was COVAX’s plan to grow and diversify its portfolio to 10-12 vaccines but at the start of the year when approved vaccines were only slowly coming online, we had very few options available to us,” she said.
(Reporting by Kate Kelland; Additional reporting by Francesco Guarascio in Brussels and Ludwig Burger in Frankfurt; Editing by Pravin Char)
Thanks to Kobach, Trump and conservative think tank, we know extent of voter fraud
Charles Hammer May 20, 2021
We Kansans owe Kris Kobach warm thanks for his greatest triumph: He proved that voter fraud is virtually nonexistent in our state. He achieved that by fiercely striving to prove the opposite.
In 2010 he got himself elected as Kansas secretary of state, then won legislative authority to prosecute illegal voters — a power no equivalent state official elsewhere holds.
He secured a 2013 law requiring that those registering to vote prove they are American citizens. His bar to voting was among the most severe in the nation until overruled in federal court.
Kobach recently filed to run for Kansas attorney general in the next election.
So how many fraudulent voters did Kobach’s dragnet convict during his eight-year tenure in office? Just nine. Nine convictions in a state with nearly 2 million registered voters. Among those were older citizens who mistakenly voted in two different places where they owned property.
A college student filled out an absentee ballot for her home state before voting months later in Kansas, both times for Trump. Steve Watkins, a former Republican congressman, was charged with three felony voting offenses and got off with diversion.
The Heritage Foundation, a conservative think tank, supports the arguments of Donald Trump and Kobach. Going back as far as 2005, Heritage lists 15 convictions for voter infractions in Kansas, presumably including those from the Kobach era. Over 15 years, one offense per year.
The Heritage website also reports 1,322 “proven instances of voter fraud” in the United States since the early 1980s. How could America have passed 40 years with a measly 1,322 proven instances of voter fraud? Among our 168 million registered voters?
Both for Kansas and the nation, the rate of fraud has been less than one one-thousandth of 1%. Would that we religious Americans sinned at such a microscopic rate.
Fully armed, Trump, Kobach and the Heritage Foundation marched out on an elephant hunt and bagged a gnat.
But, see, there must be horrendous voter fraud. Otherwise, how can Republicans defend their gerrymandering of voting districts so they win even when they lose? How can they defend suppression of votes from minorities, the elderly and young people?
Only fraud can justify shutting down polling places, banning drop boxes, cutting short mail voting and requiring notary public signatures on such ballots — make it, in other words, very hard for certain people to vote.
Here’s another high-flying way they strive to overcome “fraud.” The U.S. president telephones the Georgia secretary of state and says: “So, look…I just want to find 11,780 votes, which is one more than we have. Because we won the state…And there’s nothing wrong with saying, you know, that you’ve recalculated.”
But what if the man answers: “Well, Mr. President…the data you have is wrong”? Then direct threats are necessary. “You know, that’s a criminal,” says the president, “that’s a criminal offense….”
Then there’s the oft-repeated claim by Kobach and others that undocumented immigrants swarm to the polls and elect Democrats.
My research on this went only as far as the Heritage Foundation’s own list of their illegal Kansas voters’ last names: Watkins, Garcia, Christensen, Criswell, Doyle, Farris, Hannum, Kilian, Weems, Wilson, Gaedke, Kurtz, Duncan, Scherzer and McIntosh. Not a plethora of Hispanic last names there.
The Heritage tally also includes one Hispanic name, Lleras-Rodriguez, among 17 voter fraud cases in Missouri.
I’m tender myself on the immigrant issue since I’m half German. My father embarked from Hamburg just five years before Adolf Hitler seized power in 1933.
As an immigrant hater, Trump should be tender himself since his grandfather was German and his mother immigrated from Scotland. Two of his three wives, one now an ex-wife, immigrated from Eastern Europe.
Long before he died in 1974 my dad (naturalized as an American citizen in 1934) got to feeling easy about his origins. I fondly remember him tilted back in his green recliner, puffing his pipe and musing, as we immigrants often do, on who should be Americans.
“That’s de trouble mit this country,” he would say with a grin. “We got too dang many foreigners. They gettin’ all de good jobs. Ha, ha, ha!”